Postoperative Incidence of Atrial Fibrillation Following Cardiac Surgery

Fundación Cardioinfantil Instituto de Cardiología

Status: Completed

Conditions: Cardiac Surgery; Atrial Fibrillation (AF); Hypomagnesemia

Study type: Observational

Funder types: Other

Identifiers

NCT06855550

2023PROCCA0043 (Other Identifier)

Details and patient eligibility

About

Introduction: Postoperative atrial fibrillation is one of the most frequent complications in cardiac surgery, with an expected incidence of more than 50% following valve surgery. Hypomagnesemia is also likely to be observed in the postoperative period, and several studies have suggested that it could be related to the incidence of postoperative atrial fibrillation. In this study, via a prospective design and adjustment for multiple covariates, the investigators will seek to determine whether plasma magnesium levels are independently associated with the appearance of postoperative atrial fibrillation.

Methods: An analytical design involving a concurrent cohort will be carried out in a high-complexity hospital with a cardiovascular focus. Serial postoperative plasma magnesium measurements will be included as independent variables in a logistic regression model to determine their association with atrial fibrillation after adjusting for multiple covariates.

Enrollment: 435 patients

Sex: All

Ages: 18+ years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Adults in postoperative cardiac surgery

Exclusion criteria

• Preoperative atrial fibrillation
• Without complete information regarding plasmatic magnesium postoperative measurements

Trial design

435 participants in 1 patient group

Postoperative cardiac surgery

Description:

Patients who will undergo elective cardiac surgery of any kind will be included, except those with a history of preoperative atrial fibrillation, urgent/emergency surgery, or those who will undergo maze surgery (alone or in combination with other procedures). Magnesium levels will be measured immediately after surgery and every subsequent 12-24 hours during the stay in the intensive care unit. Each patient will be followed up, and morbidity and mortality will be recorded through in-hospital evaluation or up to 30 days postoperatively (whichever occurs first). Follow-up will be performed by a member of the research team who will be blinded to the postoperative magnesium levels. Preoperative evaluation, premedication, anesthetic/surgical technique, and postoperative care will conducted according to institutional protocols; no modifications of any kind will be made for the participants.