ClinicalTrials.Veeva

Menu

Postoperative Infectious Complications Calculator for Elderly Patients

W

Weidong Mi

Status

Completed

Conditions

Geriatrics
Prediction
Postoperative Infection

Study type

Observational

Funder types

Other

Identifiers

NCT06265493
PLAGH-AOC-L02

Details and patient eligibility

About

The investigators established a first-ever convenient scoring system for clinicians to assess the risk of Postoperative infectious complications (PICs) for elderly patients. Our scoring system can aid in the early detection of potential risks for postoperative infections. Higher-score patients were more likely to experience postoperative infections.

Full description

Background:

Postoperative infectious complications (PICs) are related to increased morbidity, mortality, and costs, especially in elderly patients. However, published prediction models of PICs are rarely based on elderly patients.

Objective:

The study wanted to identify practical and valuable variables that could be used to predict postoperative infections and establish a convenient scoring system for clinicians to assess the risk of such conditions in elderly patients.

Methods: Data from 2 population-based cohorts of elderly patients undergoing non-cardiac and non-neurology surgery were used to derive and validate multivariable logistic regression models. The risk prediction models were derived from 37230 patients hospitalized in the First Medical Center of the Chinese PLA General Hospital (January 2012 - August 2018). The risk prediction models were externally validated with data from a cohort of 10252 patients hospitalized in Henan Provincial People's Hospital (November 2014 to May 2022).

Enrollment

37,230 patients

Sex

All

Ages

65+ years old

Volunteers

No Healthy Volunteers

Inclusion criteria

  1. age ≥ 65 years and
  2. patients undergoing surgery with anesthesia.

Exclusion criteria

  1. patients undergoing neurosurgery or cardiac surgery,
  2. preoperative infectious diseases, and
  3. patients with ≥50% of data missing.

Trial design

37,230 participants in 2 patient groups

derivation cohort
Description:
29785 in the derivation cohort
internal validation cohort
Description:
7445 in the internal validation cohort

Trial contacts and locations

1

Loading...

Data sourced from clinicaltrials.gov

Clinical trials

Find clinical trialsTrials by location
© Copyright 2026 Veeva Systems