Postoperative New-onset Proteinuria and Adverse Outcomes.

Yaozhong Kong

Status: Completed

Conditions: Mortality; Proteinuria; Surgery

Treatments: Other: proteinuria

Study type: Observational

Funder types: Other

Identifiers

NCT06339229

FSYYY-2024-12

Details and patient eligibility

About

We aimed to assess the association between postoperative new-onset proteinuria, all-cause mortality, and decline in kidney function in Chinese people who underwent surgery. The exposure variable was the dipstick proteinuria values from the initial postoperative urinalysis within 30 days after surgery, categorized as negative, trace, 1+, and ≥2+. The primary outcome was 30-day mortality. The secondary outcomes included 1-year mortality and composite kidney outcome assessed using the postoperative estimated glomerular filtration rate.

Enrollment: 2,983,899 patients

Sex: All

Ages: 16+ years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• surgery patients

Exclusion criteria

• kidney or urinary surgery
• missing urinalysis results
• dipstick proteinuria indicated a value of "≥ trace" at least once preoperatively
• with dialysis, end-stage renal disease, or with urinary tract infection at baseline
• missing follow-up information

Trial design

2,983,899 participants in 1 patient group

surgery patients

Treatment:

Other: proteinuria