Postoperative Pain in Endodontic Therapy

T.C. ORDU ÜNİVERSİTESİ

Status: Completed

Conditions: Postoperative Pain; Endodontic Disease

Treatments: Device: PUI Group; Device: EDDY Group

Study type: Interventional

Funder types: Other

Identifiers

NCT06741592

ODU-MUTLU-001

Details and patient eligibility

About

The goal of this clinical trial is to evaluate the change in postoperative pain in mandibular premolar and first molar teeth with asymptomatic apical periodontitis when using EDDY and passive ultrasonic irrigation activation methods.

The null hypothesis is: "There is no difference in postoperative pain after root canal treatment between the irrigation activation systems in mandibular first molars and premolar teeth."

Enrollment: 57 patients

Sex: All

Ages: 18 to 55 years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

• Patients aged between 18 and 55 years, medically healthy, and free from systemic diseases.
• Patients without pregnancy or breastfeeding status.
• Patients diagnosed with asymptomatic apical periodontitis confirmed through radiographic and clinical examination.
• Patients not having a regular intake of analgesic or anti-inflammatory drugs within the last 12 hours.
• Patients lacking a history of drug allergies.
• Teeth free from calcifications, resorptions, periodontal problems, incomplete root development, a history of endodontic treatment, traumatic occlusion, or severe coronal destruction.
• Teeth with a root canal curvature of 5° or less.
• Mandibular premolars and first molars.

Exclusion criteria

• Teeth where the apical area could not be reached with a #8K file.
• Teeth with an apical diameter larger than #20K file.
• Patients with a Periapical Index (PAI) score of 1 or 2.
• Teeth having extra canals.
• Teeth requiring a second local anesthesia during treatment.
• Teeth where a file fractured within the canal during preparation.
• Vital teeth.
• Patients reporting preoperative pain.
• Teeth showing clinical symptoms such as percussion or palpation sensitivity.
• Teeth with persistent purulent discharge.

Trial design

Primary purpose: Treatment

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: Double Blind

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57 participants in 3 patient groups

EDDY Group

Experimental group

Description:

The effect of the EDDY device, preferred for root canal irrigation activation, on postoperative pain formation

Treatment:

Device: EDDY Group

PUI Group

Experimental group

Description:

The effect of the passive ultrasonic activation method, preferred for root canal irrigation activation, on postoperative pain formation

Treatment:

Device: PUI Group

Control Group

No Intervention group

Description:

Root canal treatment performed with conventional irrigation without the use of any activation method