Postoperative Symptoms in Chinese Liver Cancer Patients: Network Analysis (PSC-LCNA)

Mengmeng Yuan

Status: Terminated

Conditions: Application of Network Analysis as a Crucial Component of Cancer Care; Patients With Primary Liver Cancer (PLC) Undergoing Curative Surgical Procedures; Importance of Identifying Core Symptoms for Improving Symptom Management in PLC Patients

Treatments: Other: postoperative symptoms

Study type: Observational

Funder types: Other

Identifiers

NCT06419478

2023AH050604 (Other Grant/Funding Number)

83242306

Details and patient eligibility

About

Patients with primary liver cancer (PLC) experience a range of symptoms in the early postoperative period. Symptoms include cancer-related symptoms and adverse effects of treatment. Exploring the core symptoms and their dynamics in the early post-hepatectomy patients may help provide better symptom management programs. The purpose of this study was to identify the core symptoms in early post-hepatectomy patients and to explore the trajectory of their dynamics. During the period from March 2021 to September 2022, a total of 281 patients diagnosed with PLC and undergoing radical curative surgery were recruited from the hepatobiliary surgery departments of two hospitals in Eastern China, among whom 249 individuals (88.60%) agreed to participate in the study. A comprehensive symptom assessment was administered to the patients 1-2 days after surgery (T1) and 1-2 days before discharge (T2). Network analysis was used to identify core symptoms in early post-hepatectomy patients based on symptom severity.

Enrollment: 249 patients

Sex: All

Ages: 40 to 90 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Eligible patients were ≥18 years of age; had a diagnosis of primary liver cancer based on pathologic examination; were receiving the first hepatectomy; were conscious, spoke Chinese, and had basic communication skills.

Exclusion criteria

• Exclusion criteria include concurrent malignant tumors, mental disorders, or consciousness impairments, as well as participation in other clinical interventions.

Trial design

249 participants in 1 patient group

postoperative symptoms

Description:

Investigation of postoperative symptoms in eligible patients undergoing liver resection at two time points

Treatment:

Other: postoperative symptoms