Postpartum Uterotonic Administration

Bagcilar Training and Research Hospital

Status: Unknown

Conditions: Postpartum Bleeding

Treatments: Drug: Oxytocin

Study type: Interventional

Funder types: Other

Identifiers

NCT02495272

Kanuni-Bagcilar

Details and patient eligibility

About

The investigators are planning to determine the effect of the timing of oxytocin administration on the amount of blood loss, necessity for additional medical or surgical interventions.

Full description

The investigators are studying the effects of the timing of intramuscular oxytocin administration in the third stage of labour. The investigators are measuring the postpartum blood loss: quantitatively in the postpartum 1st hour and indirectly by the decrease in the hemoglobin-haematocrit levels in the postpartum 24th hour. The investigators are monitoring the length of the third stage of labour, and the need for extra uterotonics and/or surgical interventions.

Enrollment: 330 estimated patients

Sex: Female

Ages: 18 to 40 years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

• Cephalic presentation
• Singleton pregnancy
• Gestational age >35 weeks,
• In active labour.
• Expected fetal birth weight 2500-4500 grams.

Exclusion criteria

• Acute Fetal Distress
• Conversion to abdominal delivery
• Persistent high blood pressure (>140/90mmHg)
• Placenta Previa
• Ablatio placenta
• Previous C-Section
• Uterine scar
• Postpartum hemorrhage in previous pregnancies.
• Hydramnios
• Maternal infection
• Forceps/Vacuum Assisted deliveries
• Abnormal placentation ( Placenta accreta, increta or percreta)
• Coagulation Defects
• Hemoglobin < 8g/dl

Trial design

Primary purpose: Prevention

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: Single Blind

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330 participants in 2 patient groups

Control Group

Active Comparator group

Description:

Oxytocin 10IU im was administered after placental delivery

Treatment:

Drug: Oxytocin

Study Group

Experimental group

Description:

Oxytocin 10IU im was administered after the anterior shoulder could be seen.

Treatment:

Drug: Oxytocin