Postprandial Hypotension and Insulin Levels

Ankara Yildirim Beyazıt University

Status: Completed

Conditions: Hypoglycemia; Postprandial Hypotension

Treatments: Other: Mixed meal test

Study type: Observational

Funder types: Other

Identifiers

NCT06657287

AnkaraYBU-KARAKAYA004

Details and patient eligibility

About

The goal of this observational study is to learn about the relationship between postprandial hypotension and insulin levels in adults. The main question it aims to answer is:

Is the incidence of postprandial hypotension high in patients who undergo mixed meal test?

Is insulin level higher in individuals with postprandial hypotension compared to those without during a mixed meal test?

Patients with postprandial symptoms were scheduled for a mixed meal test, during which plasma glucose, insulin, C-peptide, blood pressure, and heart rate were measured at specific time points.

Enrollment: 111 patients

Sex: All

Ages: 18 to 65 years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

• Adults with postprandial symptoms

Exclusion criteria

• Individuals with prediabetes or diabetes,
• Those aged 65 and above,
• Patients using antihypertensive medications or with known hypertension,
• Those with active infections,
• Congestive heart failure,
• Peripheral artery disease,
• Advanced-stage dementia,
• Individuals who could not provide a history or were unable to cooperate,
• Patients using medications that could induce hypoglycemia (oral antidiabetics, insulin, beta-blockers, hydroxychloroquine, bromocriptine, etc.)
• Those with conditions that could cause hypoglycemia (uncontrolled hypothyroidism, adrenal insufficiency, growth hormone deficiency, etc.)

Trial design

111 participants in 1 patient group

Healthy adults

Description:

Adults with postprandial symptoms

Treatment:

Other: Mixed meal test