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Postprandial VLDL-TG Metabolism

University of Aarhus logo

University of Aarhus

Status

Completed

Conditions

Type 2 Diabetes

Study type

Observational

Funder types

Other

Identifiers

NCT01961024
ES-0006

Details and patient eligibility

About

In thise study, we aim to determine the effect of meal fat on VLDL-TG kinetics in type 2 diabetic and healthy subjects matched for BMI in order to elucidate the potential pathophysiological differences in VLDL-TG FA channeling towards oxidation and storage in abdominal and leg subcutaneous adipose tissue. Specifically, we want to measure, by way of fat and muscle biopsies, the quantitative postprandial storage of VLDL-TG FA's in skeletal muscle and adipose tissue in relation to a series of tissue specific proteins and enzymes that might be involved in regulating skeletal muscle and adipose tissue FA storage.

Enrollment

21 patients

Sex

Male

Ages

30 to 70 years old

Volunteers

Accepts Healthy Volunteers

Inclusion criteria

  • Written consent

Exclusion criteria

  • Known diseases
  • Alcohol abuse
  • Smoker
  • Regular use of medicine

Trial design

21 participants in 2 patient groups

Type 2 diabetic men
Age- and weight-matched controls

Trial contacts and locations

1

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Data sourced from clinicaltrials.gov

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