Posturography-assisted Vestibular Retraining for Stable Unilateral Vestibular Deficit

Eytan A. David

Status: Completed

Conditions: Dizziness; Inner Ear Disease; Equilibrium; Disorder, Labyrinth; Inner Ear Injury

Treatments: Device: Vestibular retraining with dynamic posturography; Behavioral: At-home rehabilitation exercises

Study type: Interventional

Funder types: Other

Identifiers

NCT05115032

H21-03343

Details and patient eligibility

About

People that have difficulty with balance have a higher risk of falling and reduced quality of life. Some individuals can learn to compensate using their vision, their sense of where their limbs are in space, and balance organs that are still intact. Rehabilitation exercises, which typically involve shaking and nodding of the head, are often prescribed for dizzy patients but are not effective for everyone. Our study aims to determine if specific exercises performed on footplate sensors with visual feedback is superior to traditional rehabilitation exercises done at home for improving balance and quality of life.

Enrollment: 37 patients

Sex: All

Ages: 18 to 80 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Dizziness handicap inventory score at time of enrolment over 30

• Unilateral vestibular weakness confirmed one or more of:

  • Videonystagmography showing unilateral weakness to bithermal testing of greater than 25%
  • VEMP: IAD asymmetry of greater than 40% for both cVEMP and oVEMP
  • VEMP: absence of both ocular and cervical vemp responses in one ear in the context of normal and replicable other ear
  • Or unilateral vestibular weakness idiopathic, not yet diagnosed (NYD)

• Persistent imbalance following diagnosis of resolved benign paroxysmal positional vertigo (BPPV)

• Symptomatic

• Long-standing/persistent symptoms greater than six months

Exclusion criteria

• Orthopedic deficit (eg. lower body joint dysfunction or lower joint replacement)
• Neurological deficit or proprioception deficit
• Diabetes
• Poor vision or blindness
• Fluctuating vestibular symptoms, or condition known to fluctuate eg. Menière's disease, perilymphatic fistula (PLF) or superior canal dehiscence (SDCS)
• Active benign paroxysmal positional vertigo (BPPV)
• Undergoing treatment which may affect balance or ability to stand
• Cognitive impairment that prevents understanding and responding to instructions required to complete the study
• Inability to provide informed consent

Trial design

Primary purpose: Treatment

Allocation: Randomized

Interventional model: Crossover Assignment

Masking: None (Open label)

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37 participants in 2 patient groups

Vestibular retraining with dynamic posturography

Experimental group

Description:

12 sessions, twice per week, of rehabilitation exercises last about 20 minutes, using CDP and interactive visual feedback

Treatment:

Device: Vestibular retraining with dynamic posturography

At-home rehabilitation exercises

Active Comparator group

Description:

Daily rehabilitation exercises involving nodding and shaking of the head

Treatment:

Behavioral: At-home rehabilitation exercises