Effects of Coffee Consumption on Health Among Adults

Zhejiang University

Status: Completed

Conditions: Health

Treatments: Other: Warm Water; Other: Decaffeinated Coffee; Other: Caffeinated Coffee

Study type: Interventional

Funder types: Other

Identifiers

NCT03817944

RCT-Coffee

Details and patient eligibility

About

The purpose of this study is to research the changes of typical thermal processing food intervention on health outcome, metabolites, and gut microbiota, in order to explore the molecular mechanism of interaction between maillard reaction associated hazards and complex food matrix, and provide scientific basis and reference model for combining food nutrition and safety protection.

Enrollment: 156 patients

Sex: All

Ages: 17 to 29 years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

• Non-smoking, non-occupational exposed healthy volunteers, 18.5<BMI<30 kg/m^2, were screened. If the evaluation of disease history, blood biochemistry and blood routine was normal, the volunteers were considered healthy.

Exclusion criteria

• The main exclusion criteria included people with high exposure to cold and fever, recent drug intake (including dietary supplement intake), alcohol intake, vegetarians, pregnancy, high-temperature processed meat and beverages such as coffee and milk tea.

Trial design

Primary purpose: Other

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: Triple Blind

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156 participants in 3 patient groups, including a placebo group

Warm Water

Placebo Comparator group

Description:

300 mL Warm Water per day for 8 weeks

Treatment:

Other: Warm Water

Caffeinated Coffee

Experimental group

Description:

300 mL Caffeinated Coffee per day for 8 weeks

Treatment:

Other: Caffeinated Coffee

Decaffeinated Coffee

Experimental group

Description:

300 mL Decaffeinated Coffee per day for 8 weeks

Treatment:

Other: Decaffeinated Coffee