Potential Associated Factors of Uncontrolled Hypertension

Guangdong Provincial People's Hospital (Guangdong Provincial Academy of Medical Sciences)

Status: Unknown

Conditions: Hypertension,Essential

Study type: Observational

Funder types: Other

Identifiers

NCT02723643

GDREC 2015373H

Details and patient eligibility

About

The incidence and prevalence of hypertension is increasing while the controlled rate is extremely low in China. A substantial percentage of participants with uncontrolled hypertension are correctable if potential associated factors are identified and corrected. Therefore, it is clinically relevant to investigate and identify these potential associated factors of uncontrolled hypertension so as to increase controlled rate and reduce hypertension-associated health and economic burdens in the future. Investigators plan to conduct a prospective registry study in a single-center to initially investigate the potential associated factors of uncontrolled hypertension in cardiovascular outpatient department. Furthermore, investigators plan to evaluate the effects of potential associated factors correction on hypertension controlled rate and cardiovascular outcomes.

Enrollment: 2,000 estimated patients

Sex: All

Ages: 50 to 80 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Clinic systolic and/or diastolic blood pressure above 140 and/or 90 mm Hg treating with 3 different classes of anti-hypertensive drugs (not necessarily including diuretic).

Exclusion criteria

• Known secondary hypertension,
• Pregnant women,
• Chronic kidney disease (CKD) 3 or higher,
• Has a history of connective tissue diseases,
• Has a history of any type of cancer,
• Cognitive disorder which could not finish home blood pressure monitoring,
• Has a history of coronary heart disease,ischemic stroke,transient ischemic attack or heart failure.