Potential Health Effects of Aronia Intake

Odense University Hospital

Status: Completed

Conditions: Health Effects of Aronia

Treatments: Dietary Supplement: Aronia, washout and then placebo; Dietary Supplement: Placebo, washout and then aronia

Study type: Interventional

Funder types: Other

Identifiers

NCT03405753

Lab.Reprod.Biol.-Aronia

Details and patient eligibility

About

Intervention cross-over study during which participants receive standardized amounts of aronia berry tablets or placebo for three months, then wash out for three months, then aronia tablets or placebo for three months. The potential health effects are investigated. Following parameters are measured before and after each period of tablet intake: 1) Blood pressure, 2) Lipid fractions, 3) Testosterone, 4) Phase II markers, 5) HbA1c, 6) HSCRP, 7) F2-isoprostanes, and 8) semen quality.

Enrollment: 109 patients

Sex: Male

Ages: 25 to 65 years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

• Healthy men with total cholesterol between 5 and 7 mmol/L, who do not take medication

Exclusion criteria

• Chronic diseases and intake of medication or antioxidants

Trial design

Primary purpose: Prevention

Allocation: Randomized

Interventional model: Crossover Assignment

Masking: Quadruple Blind

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109 participants in 2 patient groups, including a placebo group

Aroia

Active Comparator group

Treatment:

Dietary Supplement: Aronia, washout and then placebo

Dietary Supplement: Placebo, washout and then aronia

Placebo

Placebo Comparator group

Treatment:

Dietary Supplement: Aronia, washout and then placebo

Dietary Supplement: Placebo, washout and then aronia