Potential Role of Gastric Lavage by Paraffin Oil in Acute Aluminum Phosphide Poisoning

Sherief Abd-Elsalam

Status: Enrolling

Conditions: Toxicity, Drug

Treatments: Device: Gastric lavage with saline and sodium bicarbonate 8.4%; Device: Paraffin oil gastric lavage

Study type: Interventional

Funder types: Other

Identifiers

NCT04499885

ghada protocol

Details and patient eligibility

About

Potential Role of Gastric Lavage by Paraffin Oil in Acute Aluminum Phosphide Poisoning.

Full description

The study aims to investigate the Potential Role of Gastric Lavage by Paraffin Oil in Acute Aluminum Phosphide Poisoning: A Randomized Controlled Clinical Trial

Enrollment: 62 estimated patients

Sex: All

Volunteers: No Healthy Volunteers

Inclusion criteria

• • Patients with symptomatic acute aluminum phosphide poisoning

Exclusion criteria

• • Pregnant and lactating women

  • Asymptomatic patients with history of acute aluminum phosphide exposure.
  • Patients with ingestion or exposure to other substances in addition to aluminum phosphide.
  • Patients with other major medical conditions (e.g. cardiovascular disease, renal or hepatic failure).
  • Patients with previous medical intervention (had gastric lavage in any medical center before admission).
  • Patients with disturbed consciousness level
  • Patients with post cardiac arrest cases

Trial design

Primary purpose: Treatment

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: None (Open label)

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62 participants in 2 patient groups

Paraffin oil gastric lavafe

Active Comparator group

Description:

Gastric lavage will be initiated with 50 mL of Paraffin oil and 50 mL of sodium bicarbonate solution

Treatment:

Device: Paraffin oil gastric lavage

Saline gastric lavage

Active Comparator group

Description:

Gastric lavage with saline and sodium bicarbonate

Treatment:

Device: Gastric lavage with saline and sodium bicarbonate 8.4%