Potential Role of Gum Arabic as Immunomodulatory Agent Among COVID 19 Patients (GA&COVID19)

Al-Neelain University

Status and phase: Unknown; Phase 3; Phase 2

Conditions: COVID 19

Treatments: Dietary Supplement: Pectin; Dietary Supplement: Acacia Senegal

Study type: Interventional

Funder types: Other

Identifiers

NCT04381871

GA& COVID19

Details and patient eligibility

About

To study the efficacy of Gum Arabic as an immuno modulator and anti-inflammatory agent among COVID 19 seropositive patients..Half of participants will receive Gum Arabic and the other half will receive placebo

Full description

Randomized placebo controlled trial including COVID 19 seropositive patients will be treated with 30 gram per day for 4 weeks, compared to placebo group treated for the same duration in positive COVID 19 patients.

Blood samples will be taken first at base line level, after two weeks and after the intervention after satisfying the inclusion and exclusion criteria. The main objective is to assess the effect of Gum Arabic (acacia Senegal) on immune system among COVID-19 patients. The outcome of this project understand SARS-CoV-2 immune response in COVID patients and the effect of Gum Arabic (Acacia Senegal) consumption to counteract progression of the disease

Enrollment: 110 estimated patients

Sex: All

Ages: 5 to 90 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• COVID 19 infected as proved by real time PCR (polymerase chain reaction) .( newly diagnosed)

Exclusion criteria

• Intubated patients on parental treatment

Trial design

Primary purpose: Treatment

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: Quadruple Blind

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110 participants in 2 patient groups, including a placebo group

Intervention Group

Experimental group

Description:

This arm will receive 100% natural Gum Arabic provided in a powder form in 30-grams-dose

Treatment:

Dietary Supplement: Acacia Senegal

Control group

Placebo Comparator group

Description:

This group will be provided with pectin powder provided as one-gram-dose

Treatment:

Dietary Supplement: Pectin