Povidone-iodine Against Sodium Hypochlorite as Skin Antiseptics

Universidad de Guanajuato

Status and phase: Completed; Phase 3

Conditions: Healthy Volunteers

Treatments: Other: WHOLE GROUP OF 48 VOLUNTEERS

Study type: Interventional

Funder types: Other

Identifiers

NCT00738543

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Details and patient eligibility

About

The investigators have few options for skin antisepsis. Alternatives for povidone-iodine, which is the most commonly used agent, are costly or ineffective. To have more options, this study is needed. The investigators want to know if there are difference between the use of 10% sodium hypochlorite or 10% povidone-iodine for skin antisepsis.

Full description

Sodium hypochlorite at 10% has been widely used as antiseptic in patients on dialysis as well as for irrigation of wounds and burns. Since it has been used successfully in caring for the exit site of hemodialysis catheters, it is reasonable to propose its use for the insertion and care of central intravascular catheters, as well as for skin preparation before surgery. Alternatives for povidone-iodine, which is the agent most commonly used, are costly or ineffective. To have more options, this study is needed to know if 10% sodium hypochlorite is similar to the most common option for skin antisepsis.

Enrollment: 48 patients

Sex: All

Ages: 18+ years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

• Healthy adult volunteers.

Exclusion criteria

• History of skin allergies or atopy, as well as reactions to soaps, iodine, chlorine, or latex

Trial design

Primary purpose: Prevention

Allocation: N/A

Interventional model: Single Group Assignment

Masking: Single Blind

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48 participants in 1 patient group

Whole group of 48 volunteers

Experimental group

Description:

The arm is composed of 48 human volunteers to test 10% povidone-iodine (Isodine Solucion ®, Boehringer-Ingelheim Promeco, Mexico City), Hypochlorite 10% of electrochemical production (Exsept 10% ®, Pisa, Guadalajara, Mexico), and control.

Treatment:

Other: WHOLE GROUP OF 48 VOLUNTEERS