Povidone Iodine Irrıgation at Hip-Knee Arthroplasty

Ankara University

Status: Enrolling

Conditions: Osteoarthritis; Hyperthyroidism; Iodine Toxicity

Treatments: Procedure: Saline Solution; Procedure: PI solution

Study type: Interventional

Funder types: Other

Identifiers

NCT05599841

Orthop2180

Details and patient eligibility

About

Povidone iodine (PI) solution is an antimicrobial solution that can be used at hip and knee arthroplasty cases. It contains iodine that may be absorbed by the body. This study aims to investigate any absorption caused by PI solution.

Enrollment: 120 estimated patients

Sex: All

Ages: 18+ years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• All patients with hip/knee osteoarthritis who undergo primary arthroplasty

Exclusion criteria

• Patients with abnormal thyroid function tests in the preoperative period, a history of the previous thyroid-related disease.

Trial design

Primary purpose: Screening

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: Double Blind

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120 participants in 2 patient groups, including a placebo group

Povidone Iodine Solution

Active Comparator group

Description:

The group whom PI solution will be used at surgery

Treatment:

Procedure: PI solution

Saline Solution

Placebo Comparator group

Description:

The group whom only saline solution will be used at surgery

Treatment:

Procedure: Saline Solution