Povidone-iodine Versus Saline in Vaginal Cleansing Before Office Hysteroscopy (PISOH)

Assiut University

Status and phase: Completed; Phase 3

Conditions: Postoperative Infection

Treatments: Drug: povidone-iodine; Drug: normal saline

Study type: Interventional

Funder types: Other

Identifiers

NCT02713074

PI-S

Details and patient eligibility

About

The normal saline is used in medicine as an intravenous isotonic infusion and for cleaning wounds. It is a mild but effective cleaning agent and will not harm normal tissue, unlike many stronger antiseptics. It is available and inexpensive in comparison to povidone iodine.

Enrollment: 147 patients

Sex: Female

Volunteers: No Healthy Volunteers

Inclusion criteria

1 - All women who will subject to office Hysterosocpy for gynecological problems

Exclusion criteria

1. All patients have current vaginitis or urinary tract infection before the hysteroscopy
2. Diabetic women.
3. Women with body mass index > 25 kg/m2.

Trial design

Primary purpose: Prevention

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: Single Blind

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147 participants in 2 patient groups

Group A

Active Comparator group

Description:

povidone-iodine group

Treatment:

Drug: povidone-iodine

Group B

Active Comparator group

Description:

Normal saline group

Treatment:

Drug: normal saline