Power Spectral Analysis of EEG During Equi-MAC Inhalation Anesthesia

Kangbuk Samsung Hospital

Status and phase

Completed

Phase 3

Conditions

Anesthesia

Treatments

Drug: Sevoflurane

Drug: Desflurane

Study type

Interventional

Funder types

Other

Identifiers

NCT02872389

KBSMC 2016-07-033

Details and patient eligibility

About

The purpose of this clinical trial is to compare hypnotic effect of sevoflurane and desflurane at equal minimum alveolar concentrations using power spectral analysis of the electroencephalogram.

Full description

Volatile anesthetics vary in their relative hypnotic potency. Recent studies demonstrated that equi-minimum alveolar concentration of various volatile anesthetic agents may produce different spectral entropy or bispectral index values. However, there were no studies that demonstrate the difference of hypnotic potency using power spectral analysis of electroencephalographic signals (e.g., spectral edge frequency 95%, total power, % value of each bandage). The purpose of this clinical trial is to compare hypnotic effect of sevoflurane and desflurane at equal minimum alveolar concentrations using power spectral analysis of the electroencephalogram.

Enrollment

90 patients

Sex

All

Ages

19 to 65 years old

Volunteers

No Healthy Volunteers

Inclusion criteria

patients undergoing arthroscopic knee surgery under general anesthesia using volatile anesthetics
patients with american society of anesthesiologist physical status I, II
patients aged 19-65 years
patients obtaining written informed consent

Exclusion criteria

patients with a history of any psychiatric or neurological disease
patients who had received any medication affecting the central nervous system
patients who had received medication affecting the sympathetic or parasympathetic nervous systems
patients undergoing tracheal intubation for airway management
pregnant women