ClinicalTrials.Veeva

Menu

PPAR - Combination With Metformin

Bristol-Myers Squibb (BMS) logo

Bristol-Myers Squibb (BMS)

Status and phase

Completed
Phase 3

Conditions

Diabetes Mellitus

Treatments

Drug: Muraglitazar

Study type

Interventional

Funder types

Industry

Identifiers

NCT00162240
CV168-022

Details and patient eligibility

About

A Phase 3, Randomized, Double-blind, Placebo Controlled, Multicenter Trial to Evaluate the Safety and Efficacy of BMS-298585 in Combination with Metformin Therapy in Subjects with Type 2 Diabetes Who Have Inadequate Glycemic Control on Metformin Therapy Alone

Sex

All

Ages

18 to 70 years old

Volunteers

No Healthy Volunteers

Inclusion criteria

  • Type 2 Diabetes
  • HbA1c > - 7.0% and < - 10.0 %
  • Mean serum triglyceride < - 600 mg/dL
  • Body mass index < - 41 kg/m2
  • Fasting c-peptide > - 1.0 ng/mL

Exclusion criteria

  • History of myocardial infarction (MI)
  • coronary angioplasty or bypass graft(s)
  • valvular disease or repair
  • unstable angina pectoris
  • transient ischemic attack (TIA), cerebrovascular attack, or cerebrovascular accident (CVA) within 6 months
  • Congestive heart failure NYHA Class III and IV
  • Uncontrolled hypertension
  • History of renal disease, peripheral vascular disease (PVD), pulmonary disease, gastrointestinal disease, active liver disease or endocrine disease

Trial design

Primary purpose

Treatment

Allocation

Randomized

Interventional model

Parallel Assignment

Masking

Double Blind

Trial contacts and locations

203

Loading...

Data sourced from clinicaltrials.gov

Clinical trials

Find clinical trialsTrials by location
© Copyright 2025 Veeva Systems