Practice of Deep Venous Thrombosis Prophylaxis and Its Incidence in Patients Undergoing Gastrointestinal and Hepatobiliary Surgery

Maharajgunj Medical Campus

Status: Completed

Conditions: Gastrointestinal

Treatments: Procedure: major gastrointestinal or hepatobiliary surgery under general anesthesia

Study type: Observational

Funder types: Other

Identifiers

NCT07088575

589(6-11)E2.079/080

Details and patient eligibility

About

Recent studies from Asia have reported a wide variation in the incidence of deep vein thrombosis (DVT), ranging from 5% to 50% in patients undergoing major abdominal surgery. However, data specific to the Nepalese population remains unavailable. This study aims to evaluate current thromboprophylaxis practices and determine the incidence of DVT in Nepalese adults undergoing gastrointestinal and hepatobiliary surgery.

Enrollment: 1,530 patients

Sex: All

Ages: 18+ years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Adults aged >18 years
• Underwent major gastrointestinal or hepatobiliary surgery
• Surgery performed under general anesthesia
• Major surgery defined as any operative intervention in the abdominal or hepatobiliary region requiring general anesthesia

Exclusion criteria

• History of VTE within 3 months before surgery
• Known hypercoagulable state or congenital thrombophilia
• Diagnosis of atrial fibrillation
• Undergoing systemic cancer chemotherapy or radiotherapy within the past 15 days
• Pregnant or lactating women
• Missing information in clinical records
• Non-operated patients or those receiving conservative management
• Patients undergoing liver transplantation

Trial design

1,530 participants in 1 patient group

Patients >18 years who underwent major gastrointestinal or hepatobiliary surgery

Treatment:

Procedure: major gastrointestinal or hepatobiliary surgery under general anesthesia