Pre- and Postoperative Chest Therapy With Positive Expiratory Pressure (PEP) to Prevent Hospital-acquired Pneumonia

University Hospital Bispebjerg and Frederiksberg

Status: Enrolling

Conditions: Hip Fractures (ICD-10 72.01-72.2)

Treatments: Device: positive expiratory pressure

Study type: Interventional

Funder types: Other

Identifiers

NCT07189260

PEP trial

Details and patient eligibility

About

The goal of this clinical trial is to investigate whether pre- and postoperative treatment with systematic PEP therapy can prevent hospital-acquired pneumonia in patients with hip frac-ture. It will also learn about the barriers regarding PEP therapy in this group of patients.

• Does pre- and postoperative treatment with systematic PEP therapy prevent hospital-acquired pneumonia in patients with hip fracture?
• Which barriers do participants have regarding PEP therapy in this group of patients? Researchers will compare systematic PEP therapy to no intervention besides standard treat-ment to see if systematic therapy with PEP can prevent hospital-acquired pneumonia.

Participants will:

• Receive systematic PEP therapy during hospitalization or no intervention besides standard treatment
• Register the PEP therapy four times daily on a paper checklist. Failure to perform the treatment and the reason must also be documented on the checklist.

Enrollment: 566 estimated patients

Sex: All

Ages: 18+ years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Hip fracture regardless of age
• Cognitively well-functioning
• Able to understand the study and give informed consent
• Able to speak and understand Danish
• Resident of Region Hovedstaden or Region Sjælland

Exclusion criteria

• Cognitively impaired
• Unable to understand the study and give informed consent
• Pneumonia upon admission
• Delirium upon admission
• Pneumothorax

For patients with e.g. dementia or brain injury, the ability to give informed consent will be assessed individually.

Trial design

Primary purpose: Prevention

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: None (Open label)

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566 participants in 2 patient groups

Active

Active Comparator group

Description:

Medical therapy device

Treatment:

Device: positive expiratory pressure

Standard treatment

No Intervention group

Description:

Standard treatment