Pre-dinner vs. Post-dinner Exercise on Glycemic Control

University of Missouri (MU)

Status: Completed

Conditions: Type 2 Diabetes

Treatments: Other: exercise then meal; Other: Meal then exercise; Other: No exercise

Study type: Interventional

Funder types: Other

Identifiers

NCT02180620

exertime

Details and patient eligibility

About

With many medications we prescribe them relative to time of day or a meal. This study established if pre dinner vs post dinner exercise was more effective at altering post dinner glucose and triglyceride levels vs no exercise at all.

Full description

All participants completed three trials in a random order in which they consumed a standardized dinner meal with 1) no RE (NoRE), 2) pre-dinner RE (RE→M), and 3) post-dinner RE beginning 45 min after dinner (M→RE). Diet was standardized during the day of testing. Participants reported to the lab for testing sometime between 3 - 5:30 p.m. and upon arrival a venous catheter was inserted into a forearm vein. Frequent blood sampling, indirect calorimetry measurements, and subjective well-being measurements ensued for ~5.75 h while the participants were in the lab.

Enrollment: 13 patients

Sex: All

Ages: 25 to 55 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Obese ( body mass index 30-45 kg/m2)
• Physician diagnosed with type 2 diabetes receiving standard medical care
• Non-smokers
• Pregnancy
• Lactating mothers

Exclusion criteria

• Insulin
• Surgical weight loss
• Orthopedic limitations to exercise
• Weight loss in the previous 3 months

Trial design

Primary purpose: Other

Allocation: Non-Randomized

Interventional model: Crossover Assignment

Masking: None (Open label)

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13 participants in 3 patient groups

No exercise

Experimental group

Description:

participants will remain sedentary during testing

Treatment:

Other: No exercise

Meal then exercise

Experimental group

Description:

45 min of resistance training will be performed after a standard meal

Treatment:

Other: Meal then exercise

exercise then meal

Experimental group

Description:

45 min of resistance training will be performed prior to a standard meal

Treatment:

Other: exercise then meal