Pre-emptive Paracetamol for Prevention of Intraoperative Shoulder Tip Pain

Cairo University (CU)

Status and phase: Unknown; Phase 3; Phase 2

Conditions: Cesarean Section

Treatments: Drug: Saline Solution; Drug: paracetamol

Study type: Interventional

Funder types: Other

Identifiers

NCT04038307

MS-12-2019

Details and patient eligibility

About

the aim is to determine the efficacy of Paracetamol in reducing the incidence and severity of intraoperative shoulder pain in patients undergoing cesarean section.

Full description

pregnant females scheduled for cesarean section under spinal anesthesia will be enrolled . two groups of patents will be recruited . the study group will receive paracetamol pre operative .

Enrollment: 120 patients

Sex: Female

Volunteers: No Healthy Volunteers

Inclusion criteria

• Healthy pregnant women (ASA II) having singleton pregnancy at term (≤ 37 weeks of gestation) aged between 18 and 40 years.

Exclusion criteria

• Patients having allergy to study drug,
• gestational diabetes
• cardiovascular or biliary disorders
• asthma
• renal impairment
• preeclampsia
• any chronic pain condition or trauma in the shoulder, forearms or upper limbs
• patients with any contraindication to SA were excluded from the study.

Trial design

Primary purpose: Prevention

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: Triple Blind

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120 participants in 2 patient groups, including a placebo group

control

Placebo Comparator group

Description:

will receive 100 ml of saline

Treatment:

Drug: Saline Solution

paracetamol group

Experimental group

Description:

will receive 1gm paracetamol (100ml)

Treatment:

Drug: paracetamol