Pre-emptive Quadratus Lumborum Block for Laparoscopic Bariatric Surgery

Ain Shams University

Status: Completed

Conditions: Postoperative; Pain

Treatments: Drug: Bupivacaine; Procedure: US-guided Quadratus lumborum block.; Drug: Saline

Study type: Interventional

Funder types: Other

Identifiers

NCT04294329

FMASU R 18/2017

Details and patient eligibility

About

The purpose of this study was to determine the effectiveness of pre-emptive Quadratus lumborum block on intra, postoperative pain assessment and opioid requirements in laparoscopic bariatric procedures.

Enrollment: 30 patients

Sex: All

Ages: 18 to 50 years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

Patients included in this study are

• Both genders
• Age between 18-50 years
• Those undergoing laparoscopic bariatric surgery (as laparoscopic sleeve gastrectomy or gastric bypass).
• BMI ≥ 35 Kg/m2 with comorbidity or ≥ 40 Kg/m2 without comorbidity.

Exclusion criteria

Patients excluded from this study were

• those with obstructive sleep apnoea and/or Pickwickian syndrome.
• if the laparoscopy procedure was converted to laparotomy.
• patients suffering from known coagulation defects.
• known hypersensitivity to bupivacaine, or those with contraindication to the use of NSAIDS.
• Presence of sepsis at the site of injection.

Trial design

Primary purpose: Prevention

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: Triple Blind

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30 participants in 2 patient groups, including a placebo group

Group Quadratus lumborum block with bupivacaine

Experimental group

Description:

After induction of anesthesia a QLB (quadratus lumborum block) will be performed by using ultrasound machine where a solution of 0.25% bupivacaine 0.2 ml /kg (lean body weight) is used on each side with care not to exceed the toxic dose.

Treatment:

Drug: Bupivacaine

Procedure: US-guided Quadratus lumborum block.

Group Quadratus lumborum block with saline

Placebo Comparator group

Description:

After induction of anesthesia a QLB (quadratus lumborum block) will be performed by using ultrasound machine.A volume of 0.2ml/kg normal saline will given for each side.

Treatment:

Procedure: US-guided Quadratus lumborum block.

Drug: Saline