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Pre-meal Planning and Expected Satiety

U

University Hospital Tuebingen

Status

Unknown

Conditions

Adiposity

Study type

Observational

Funder types

Other

Identifiers

Details and patient eligibility

About

Obesity is considered to be caused by an imbalance between energy expenditure and energy intake. A major determinant of our daily energy intake is the size of the meals that we consume. It has been suggested that decisions about portion sizes are often made in advance, before a meal begins. This pre-meal planning is considered to especially depend on the estimated 'expected satiety' and 'expected satiation' of different foods. Further, also factors like weight concern and palatability of the food might have their influence on meal size selection. In general, it is not clear how these factors are integrated during pre-meal planning and which brain networks are involved in these decisions/this process. Thus, the investigators plan to study pre-meal planning in healthy, normal-weight and overweight/obese individuals with functional magnetic resonance imaging under different cognitive instructions including pleasure, expected satiety and self-control in terms of health consequences. The investigators will explore the neural networks involved in pre-meal planning and expect them to be modulated by the before mentioned factors. Further, the investigators plan to explore gender differences and expect that female subjects will select smaller portion sizes especially in the self-control condition as they are often more concerned about their weight/health. Finally, the investigators will explore differences between lean and overweight subjects to elucidate factors that might lead to increased meal sizes in overweight subjects.

Enrollment

60 estimated patients

Sex

All

Ages

18 to 35 years old

Volunteers

Accepts Healthy Volunteers

Inclusion criteria

  • body mass index: 18-25 kg/m²; 25-35 kg/m²,
  • right-handed,
  • age: 18-35 years.

Exclusion criteria

  • functional magnetic resonance imaging contraindications,
  • claustrophobia,
  • self-reported eating disorders,
  • vegan or vegetarian diet, food allergies,
  • intake of antidepressants,
  • metabolic disorders.

Trial design

60 participants in 2 patient groups

Lean
Description:
body mass index: 18-25 kg/m²
Overweight/Obese
Description:
body mass index: \>25 kg/m²

Trial contacts and locations

1

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Central trial contact

Hege

Data sourced from clinicaltrials.gov

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