Pre-operative Blood Lipid Level and Post-operative Major Adverse Cardiac Event

Peking University

Status: Completed

Conditions: Postoperative Complications; Lipid Metabolism Disorders

Treatments: Diagnostic Test: laboratory test

Study type: Observational

Funder types: Other

Identifiers

NCT03344224

LMACE

Details and patient eligibility

About

Whether the pre-operative blood lipid level and post-operative cardiovascular events is associated is unknown. This study is to find out the main blood lipid and relative protein level change and the post-operative cardiovascular events occurrence.

Full description

The participants collected data from their hospital.Patients under going non-cardiac surgery were collected. Data of Triglycerides, cholesterol, Low-density lipoprotein and High-density lipoprotein were collected perioperatively. The postoperative major cardiovascular and cerebral events were also identified and collected. Other data including perioperative information and surgeries and anesthesia data were gathered.

Logistic regression models were built and selected. Independent risk factors relative to postoperative major cardiovascular and cerebral events were screened and identified. different levels of Triglycerides, cholesterol, Low-density lipoprotein and High-density lipoprotein were analysed.

Enrollment: 50,000 patients

Sex: All

Ages: 18 to 100 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• non-cardiac surgery patients with preoperative blood lipid tests

Exclusion criteria

• electronic records missing or peri-operative data missing

Trial design

50,000 participants in 2 patient groups

normal blood lipid/protein group

Treatment:

Diagnostic Test: laboratory test

abnormal blood lipid/protein group

Treatment:

Diagnostic Test: laboratory test