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Pre-operative Rehabilitation Exercise Program for Total Knee Arthroplasty (PREP)

U

University of Alberta

Status

Completed

Conditions

Osteoarthritis
Rheumatoid Arthritis

Treatments

Other: Usual care
Other: Exercise

Study type

Interventional

Funder types

Other

Identifiers

NCT00493142
B-060605

Details and patient eligibility

About

The purpose of this study is to determine whether a pre-operative home rehabilitation exercise program designed for knee replacements is more effective than pre-operative usual care.

Full description

Patients with lower levels of function prior to total knee arthroplasty (TKA) attain lower functional endpoints after surgery. Therapeutic exercise improves function in patients with arthritis of the knee, yet little evidence has examined the impact of pre-operative exercise for TKA.

Single blinded randomized clinical trial comparing a pre-operative home exercise program to pre-operative usual care for patients who are waiting for TKA.Comparison group is usual care within the health region which does not include pre-operative rehabilitation program.

Primary outcome: WOMAC function subscale. Secondary outcomes: 1) quality of life; 2) ambulation; 3) self-efficacy; 4) anxiety; 5) patient satisfaction; 6) cost-effectiveness of this intervention.

Total Enrollment: 230 patients

If the intervention improves function prior to surgery, results will be clinically applicable for patients waiting for surgery

Enrollment

240 patients

Sex

All

Ages

50+ years old

Volunteers

No Healthy Volunteers

Inclusion criteria

  • primary unilateral total knee arthroplasty
  • poor functional status (WOMAC=50 or greater)
  • 50 yrs or older
  • reside within health region
  • understands English

Exclusion criteria

  • unicompartmental total knee arthroplasty
  • revision surgery

Trial design

Primary purpose

Treatment

Allocation

Randomized

Interventional model

Parallel Assignment

Masking

Double Blind

240 participants in 2 patient groups

Usual care
Active Comparator group
Description:
Usual care
Treatment:
Other: Usual care
Exercise
Experimental group
Description:
Exercise
Treatment:
Other: Exercise

Trial contacts and locations

1

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Data sourced from clinicaltrials.gov

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