Pre-pectoral Tissue Expander and Acellular Dermal Matrix for a Two-stage Muscle Sparing Breast Reconstruction

Rossella Elia, MD PhD

Status: Enrolling

Conditions: Breast Cancer

Treatments: Procedure: breast reconstruction

Study type: Observational

Funder types: Other

Identifiers

NCT06374628

0001

Details and patient eligibility

About

The aim of the research is to evaluate clinical outcomes of a two stage muscle sparing prepectoral breast reconstruction using tissue expander (TE) entirely covered by an ADM. The authors aim to report surgical indications, technical tips, clinical and histological outcomes with the final objective of delineate a decision-making algorithm for immediate prosthetic breast reconstruction.

Enrollment: 44 estimated patients

Sex: Female

Volunteers: No Healthy Volunteers

Inclusion criteria

• unilateral or bilateral mastectomy followed by two stage breast reconstruction with subcutaneous tissue expander and Acellular Dermal Matrix (ADM)
• risk-reducing mastectomies followed by two stage breast reconstruction with subcutaneous tissue expander and ADM

Exclusion criteria

• partial or total submuscular tissue expander placement,
• tissue expander placement in conjunction with latissimus dorsi muscle flap or without ADM, -delayed reconstructions
• previous breast surgery