Pre-probiotic Supplementation for Post-covid Fatigue Syndrome (STOPPFATIQUE)

University of Novi Sad, Faculty of Sport and Physical Education

Status

Completed

Conditions

Long COVID

Treatments

Dietary Supplement: Dietary Supplement: Experimental

Dietary Supplement: Dietary Supplement: Placebo

Study type

Interventional

Funder types

Other

Identifiers

NCT06013072

2022-03-23_CFS

Details and patient eligibility

About

The goal of this randomized controlled double-blind parallel-group interventional trial is to evaluate the effects of of dietary supplementation with a pre-probiotic on patient- and clinician-reported outcomes, and brain tissue metabolism in patients with post-covid fatigue syndrome.

Enrollment

32 patients

Sex

All

Ages

18 to 65 years old

Volunteers

No Healthy Volunteers

Inclusion criteria

Age 18 - 65 years
Covid-19 positive test within last 3 months (as documented byvalid PCR or antigentest
Moderate-to-severe fatigue (20-MFI test total score > 43.5)
At least one of additional covid-19 related symptoms (anosmia,ageusia,breathingdifficulties,lungpain, body aches, headaches, difficulties concentrating etc.)

Exclusion criteria

Other pulmonary and cardiovascular conditions
History of dietary supplement use during the past 4 weeks
Organic gastrointestinal (GI) disorders such as inflammatory bowel disease, coeliac disease, eosinophilic disorders, or current infection of the GI tract.
Bowel surgery or short bowel syndrome.
Medication or supplement which can impact the gut microbiome, including: antibiotics, antimicrobials, or antifungals in the two months
Probiotic or prebiotic supplements in the last 4 weeks