Pre-sleep Macros on Sleep Quality and Recovery

Florida State University

Status: Completed

Conditions: Sleep

Treatments: Dietary Supplement: Casein protein; Dietary Supplement: a-lactalbumin protein; Dietary Supplement: Carbohydrate; Dietary Supplement: Placebo

Study type: Interventional

Funder types: Other; Industry

Identifiers

NCT06102460

STUDY00004409

Details and patient eligibility

About

The goal of this clinical trial is to assess the effect of eating before bed (2 hours after dinner, 30mins before bed) and the effects this has on sleep and recovery measures in elite female athletes.

Participants will be randomized to 4 possible groups in a double-blind randomized cross over design. Each group will ingest 40 grams of one of the following nutrients as a liquid shake for 3 consecutive nights:

1. Casein Protein
2. a-lactalbumin Protein
3. Carbohydrate
4. Placebo

There will be at least 1 week washout period between each intervention.

Sleep and recovery outcome measures will be obtained through a WHOOP 4.0 wearable healthy tracking device. Subjective sleep and recovery will be obtained through subjective questionnaires. Food will be logged by participants on intervention days. Blood glucose will be measured using continuous glucose monitors.

Enrollment: 20 patients

Sex: Female

Ages: 18 to 25 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• NCAA Division I female athlete
• Wearing WHOOP 4.0 device for >3 months

Exclusion criteria

• Musculoskeletal injuries limiting participation in regular team practice.
• Cardiometabolic diseases limiting participation in regular team practice.
• Pre-diagnosed sleep condition that would negatively affect sleep quality or quantity (sleep apnea, restless leg syndrome, night-feeding syndrome)
• Allergy to any dietary supplement used in protocol - e.g., lactose intolerant.
• Use of sleep aids such as but not limited to, melatonin.

Trial design

Primary purpose: Other

Allocation: Randomized

Interventional model: Crossover Assignment

Masking: Double Blind

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20 participants in 4 patient groups, including a placebo group

Casein Protein

Active Comparator group

Description:

Each participant will consume a serving of casein protein mix.

Treatment:

Dietary Supplement: Casein protein

a-lactalbumin

Active Comparator group

Description:

Each participant will consume a serving of a-lactalbumin protein mix.

Treatment:

Dietary Supplement: a-lactalbumin protein

Carbohydrate

Active Comparator group

Description:

Each participant will consume a serving of carbohydrate mix.

Treatment:

Dietary Supplement: Carbohydrate

Placebo

Placebo Comparator group

Description:

Each participant will consume a serving of a placebo mix.

Treatment:

Dietary Supplement: Placebo