Pre-therapeutic Validation of the Virtual Reality-based Exposure Scenario for CBT "ReVBED" for the Induction of Food Craving in Patients With Bulimia and Binge Eating Disorder (BED) (RevBED)

Centre Hospitalier Universitaire de Saint Etienne

Status: Completed

Conditions: Binge-Eating Disorder; Bulimia Nervosa

Treatments: Behavioral: experimentation of the virtual reality "RevBED"

Study type: Interventional

Funder types: Other

Identifiers

NCT05385653

ANSM (Other Identifier)

21CH086

Details and patient eligibility

About

Food craving is a major therapeutic issue in Eating Disorders with binge eating: the Bulimia Nervosa and the Binge Eating Disorder (BED). Food craving is linked to compulsive eating and its apprehension is currently based on classic Cognitive and Behavioural Therapies (CBT). However, it remains difficult to induce in therapy and a significant number of patients do not respond to classic CBTs. The development of exposure scenarios for CBT in virtual reality (VR) has allowed a gain in efficacy and in particular therapeutic effects lasting longer after treatment. Nevertheless, the stimuli used are often simple food visuals and insufficiently consider the many factors influencing food craving (physical, psychological, socio-environmental...) and VR immersion is still limited by the use of 3D laptops (fixed) rather than wireless headsets.

Full description

Eating Disorders-specialized clinicians from Saint-Etienne University Hospital Center (CHU) and VR-specialized engineers from National School of Engineering of Saint-Etienne (ENISE) therefore collaborated in the creation of ReVBED, a VR-based exposure scenario for CBT for the induction of food craving in eating disorders with binge eating. ReVBED offers successive exposures to multimodal stimuli in a coherent scenario and in an immersive virtual environment via a wireless VR headset.

Our first objective is to validate the effectiveness of our scenario in inducing food craving in patients with bulimia and BED.

Enrollment: 60 patients

Sex: Female

Ages: 18+ years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

• Patients: who meet Diagnostic and Statistical Manual of Mental Disorders (DSM)-5 criteria for Bulimia Nervosa or Binge Eating Disorder
• Controls: paired to patients on age and level of education

Exclusion criteria

• Patients and controls:
• Under legal protection measure (guardianship, curatorship or safeguard of justice)
• Having a treatment being established and / or not stabilized (declarative) able to alter the physiological data recorded and the answers to the self-questionnaires
• Having one or more sensory deficit(s) or disorder(s) incompatible with the use of VR equipment (declarative)
• Patients: who have already benefited from specific care targeting food craving (declarative) Controls: with a score greater than or equal to 88 on the Bulimia Test (BULIT)

Trial design

Primary purpose: Other

Allocation: Non-Randomized

Interventional model: Parallel Assignment

Masking: None (Open label)

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60 participants in 2 patient groups

patients with bulimia or binge eating disorder

Experimental group

Description:

patients with bulimia or binge eating disorder

Treatment:

Behavioral: experimentation of the virtual reality "RevBED"

control

Other group

Description:

paired healthy controls

Treatment:

Behavioral: experimentation of the virtual reality "RevBED"