Precision Antimicrobial STewardship for Clostridioides DIfficile Prevention (PASTCDI)

Intermountain Health Care, Inc.

Status: Completed

Conditions: CDI

Treatments: Other: CDI-risk Classification Tool

Study type: Observational

Funder types: Other

Identifiers

NCT05508607

1051390

Details and patient eligibility

About

To decrease CDI incidence by implementing an electronic health record-integrated CDI-risk classification tool for Clostridioides difficile infection (CDI) to focus a bundle of antimicrobial stewardship (AMS) CDI prevention recommendations on high-risk patients.

Full description

This study aims to use a pre/post implementation design to evaluate the use of a novel risk classification tool to improve existing methods of identifying patients eligible for routine antimicrobial stewardship (AMS) care processes targeting reduction of Clostridioides difficile infection (CDI). Antimicrobial stewardship is an established, evidence-based quality improvement program that is required by The Joint Commission and a condition of participation by the Centers for Medicare and Medicaid. AMS processes of care are evidence based, supported by published research demonstrating outcomes benefits, are recommended by national guidelines and are not investigational. Treatment decisions remain at the discretion of clinicians and patients

Enrollment: 13,319 patients

Sex: All

Ages: 18+ years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• adult acute care patients identified as high-CDI risk by the CDI risk classification tool. This sub-group represents approximately 6% of all acute care admissions

Exclusion criteria

• Behavioral health units
• Inpatient rehabilitation units
• Labor and Delivery units
• Same day surgery and observation units

Trial design

13,319 participants in 2 patient groups

Pre-Implementation

Post-Implementation

Treatment:

Other: CDI-risk Classification Tool