Precision Immunology to Determine the Immune Response in Patients With COVID-19

University of Bonn

Status: Unknown

Conditions: SARS-CoV 2; COVID

Treatments: Other: Blood draw

Study type: Observational

Funder types: Other

Identifiers

NCT04360733

BOST-03

Details and patient eligibility

About

To better understand the immune response to SARS-CoV-2 infection, we devised a precision immunology approach to systematically study the immune function of different patient cohorts

Enrollment: 200 estimated patients

Sex: All

Ages: 18+ years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

• SARS-Cov2 positive PCR

Exclusion criteria

• pregnancy

Trial design

200 participants in 4 patient groups

asymptomatic Covid-19

Description:

Patients with confirmed SARS-CoV2 PCR but no clinical symptoms

Treatment:

Other: Blood draw

symptomatic Covid-19

Description:

Patients with confirmed SARS-CoV2 PCR and light clinical symptoms

Treatment:

Other: Blood draw

severe Covid-19

Description:

Patients with confirmed SARS-CoV2 PCR and severe clinical symptoms with ICU admission

Treatment:

Other: Blood draw

healthy controls

Description:

Persons with negative SARS-CoV2 PCR

Treatment:

Other: Blood draw