Precision Medicine of Diabetes Program in China (PDC)

Central South University

Status: Enrolling

Conditions: Diabetes

Treatments: Other: no intervention

Study type: Observational

Funder types: Other

Identifiers

NCT06320600

PDC

Details and patient eligibility

About

The prevalence of diabetes has been increasing year by year. According to the International Diabetes Federation (IDF) statistics in 2021, the global number of people with diabetes has reached 537 million. The patient population is large and heterogeneous, and precise diagnosis and treatment of diabetes patients have been a focus of attention. The objective of this study is to clarify the current status of precision classification and diagnosis of diabetes patients through retrospective and prospective cohort studies, and to establish a model for precision classification and diagnosis of diabetes, improving the accuracy of diabetes classification and diagnosis; based on big data of precision medicine for diabetes patients and follow-up cohorts, to establish precise diagnostic, therapeutic, and predictive methods for diabetes; and through multi-omics data analysis, to explore the potential pathogenesis of diabetes, explaining the heterogeneity of patients, and guiding individualized treatment for patients.

Enrollment: 120,000 estimated patients

Sex: All

Volunteers: No Healthy Volunteers

Inclusion criteria

• Patients diagnosed with diabetes according to WHO 1999 criteria

Exclusion criteria

• with duration more than 1 year; Diabetes has not been diagnosed by WHO standards in 1999; Absence of medical history data

Trial design

120,000 participants in 2 patient groups

Retrospective PDC cohort

Description:

The study will include diabetes patients diagnosed within 1 year (including 1 year) from both inpatient and outpatient medical record systems between January 2022 and December 2022. Each center enrolls approximately 1000 new diabetes patients annually, and it is planned to include 30 centers, with an estimated total of 30,000 participants.

Treatment:

Other: no intervention

Prospective PDC cohort

Description:

The study centers will enroll diabetes patients diagnosed within 1 year (including 1 year) from both outpatient and inpatient services between January 2024 and December 2024. Each center sees approximately 3000 new diabetes patients annually, and it is planned to include 30 centers, with an estimated total of 90,000 participants. The patients will be followed up for a period of 5 years.

Treatment:

Other: no intervention