Precision Stratification for Frailty and Cognitive Decline

National University of Singapore

Status: Enrolling

Conditions: Cognitive Decline; Frailty

Treatments: Behavioral: Centre-Based Exercise Health Session; Behavioral: Care4Senior mobile Application, Intensive Aerobic Resistance Training and Brain Health (CIRTAB)

Study type: Interventional

Funder types: Other

Identifiers

NCT07081282

NUS-IRB-2023-526

Details and patient eligibility

About

The Care4Senior mobile Application, Intensive Aerobic Resistance Training and Brain Health (CIRTAB) trial aim to test the effectiveness of an exercise, cognitive and lifestyle intervention amongst older adults over a 12-weeks trial period to prevent frailty and promote social bonding.

Full description

In the Care4Senior mobile Application, Intensive Aerobic Resistance Training and Brain Health (CIRTAB) trial, participants will use the Care4Seniors 2.0 mobile application, in which physical and cognitive exercises will be provided to participants using this digital technology. Weekly in-person group exercise and cognitive sessions will also be conducted to prevent frailty, promote social bonding, as well as reduce social isolation and loneliness.

In the long term, this new service model has the potential to transform care, contain healthcare cost inflation and increase the efficiency of the lean manpower. It will translate knowledge into practice, resulting in impactful outcomes such as better self-management and healthy longevity. The CIRTAB program will raise the awareness of health behaviour, thus attracting more older adults to engage in preventive health and thus better prepare them for healthy ageing.

Enrollment: 252 estimated patients

Sex: All

Ages: 60 to 85 years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

1. Older Adults Aged 60 to 85 years old
2. Living in the community
3. Formally diagnosed with at least one chronic disease
4. Able to communicate in either English or Mandarin

Exclusion criteria

1. Severe vision or hearing impairment
2. Diagnosed with severe cognitive impairment (e.g. dementia)
3. Diagnosed with severe psychiatric disorders (e.g. psychotic disorders, major depressive disorder)

Trial design

Primary purpose: Prevention

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: None (Open label)

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252 participants in 3 patient groups

Intervention Arm

Experimental group

Description:

Participants will receive the CIRTAB intervention three times each week over 12-weeks.

Treatment:

Behavioral: Care4Senior mobile Application, Intensive Aerobic Resistance Training and Brain Health (CIRTAB)

Active Control

Active Comparator group

Description:

Participants will receive once in centre-based exercise health programme each week over 12-weeks.

Treatment:

Behavioral: Centre-Based Exercise Health Session

Control

No Intervention group

Description:

Participants will not participate in any exercise-related or brain health-related research studies or centre-based programme during trial period.