Preclinical Study Towards an Immunotherapy in Adrenocortical Carcinoma

University of Wuerzburg

Status: Active, not recruiting

Conditions: Cushing's Syndrome; Adrenocortical Carcinoma

Study type: Observational

Funder types: Other

Identifiers

NCT00457587

Wue-Immuno-ACC-83/05

Details and patient eligibility

About

Adrenocortical carcinoma (ACC) is a rare and heterogeneous malignancy with poor prognosis. Surgical resection of the tumor is the treatment of choice. However, even after complete resection more than 80 % of patients will experience recurrence of disease. Therefore, new treatment options are urgently needed. This pre-clinical study try to lay the foundations for a successful immunotherapy in patients with ACC.

Enrollment: 150 patients

Sex: All

Ages: 18+ years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

• patients with histological proven adrenocortical carcinoma
• healthy persons as control group
• Life expectancy > 6 months

Exclusion criteria

• autoimmune diseases
• severe clinical condition