Preconditioning Volatile Anesthesia in Liver Surgery

University of Zurich (UZH)

Status: Completed

Conditions: Anesthesia

Study type: Observational

Funder types: Other

Identifiers

NCT01021228

StV 18-2008

Details and patient eligibility

About

The purpose of this study is to compare the impact and outcome of continuous volatile anesthesia to continuous intravenous anesthesia and to preconditioning volatile anesthesia in liver surgery.

Full description

Comparing the impact and outcome of continuous volatile anesthesia to continuous intravenous anesthesia and to preconditioning volatile anesthesia in liver surgery.

Enrollment: 257 patients

Sex: All

Ages: 18 to 90 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• > 18 years
• benign and malign disease
• any type of liver surgery
• inflow occlusion during the liver surgery

Exclusion criteria

• < 18 years
• participation on other interventional and treatment randomized controlled trials,
• trauma of the liver
• liver cirrhosis

Trial design

257 participants in 3 patient groups

group1

Description:

continuous volatile anesthesia (sevoflurane) during the liver resection

group2

Description:

continuous intravenous anesthesia (propofol) during the liver resection

group3

Description:

preconditioning volatile anesthesia (sevoflurane) 30 minutes before ischemia (inflow occlusion)