Predicting Cardiometabolic Risk in Mild-to-Moderate Obstructive Sleep Apnea: Inflammation vs. Apnea/Hypopnea Index

Penn State Health

Status: Invitation-only

Conditions: Obstructive Sleep Apnea

Study type: Observational

Funder types: Other

Identifiers

NCT03062748

5218

Details and patient eligibility

About

The purpose of the study is to compare the relative contribution of systemic inflammation vs. Obstructive Sleep Apnea (OSA) severity (as measured by Apnea Hypopnea Index) in predicting cardiovascular and metabolic aberrations associated with mild-to-moderate obstructive sleep apnea.

Enrollment: 196 estimated patients

Sex: All

Ages: 18+ years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Mild to moderate OSA (5≤ AHI <30)
• BMI ≤ 45
• Age ≥ 18
• Men & Women

Exclusion criteria

• AHI ≥ 30
• BMI >45
• Current use of steroids or anti-inflammatory medication
• Diagnosis of insulin dependent diabetes
• Diagnosis of autoimmune disorder
• Shiftwork
• Current use of CPAP