Predicting Colorectal Cancer - Tissue Samples to Evaluate Tumour Characteristics and Treatment Response

Sahlgrenska University Hospital

Status: Enrolling

Conditions: Colorectal Neoplasms

Treatments: Other: No intervention, just observation

Study type: Observational

Funder types: Other

Identifiers

NCT04130971

Predict

Details and patient eligibility

About

All adult patients with colorectal cancer presenting within the Sahlgrenska University Hospital or treated at any time at Sahlgrenska University Hospital are eligible and will be asked to participate. We already have biopsies taken at surgery in patients that receive surgery, but this study will include all patients and the biopsies will be taken during endoscopy for diagnosis of the primary tumour. Biopsies will then be taken during follow-up exams prior surgery but after neoadjuvant treatment. Biopsies will also be taken during surgery and in cases where surgery is not necessary biopsies will be taken regularly during follow-up exams.

Blood samples and in relevant cases urinary samples and mouth swabs will be taken at all timepoints when biopsies are taken. If it is not possible to take biopsies prior treatment blood samples will still be drawn.

Enrollment: 800 estimated patients

Sex: All

Ages: 18+ years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Colorectal cancer

Exclusion criteria

• Not colorectal cancer

Trial design

800 participants in 4 patient groups

Patients without neoadjuvant treatment

Treatment:

Other: No intervention, just observation

Patients with short course radiotherapy

Treatment:

Other: No intervention, just observation

Patients with long course chemoradiotherapy

Treatment:

Other: No intervention, just observation

Patients with short course radiotherapy and deferred surgery

Treatment:

Other: No intervention, just observation