Predicting Long-term Outcomes After Cardiac Arrest by Using Serum NGAL

Uijeongbu St. Mary Hospital

Status: Terminated

Conditions: Out-of-Hospital Cardiac Arrest

Treatments: Diagnostic Test: serum NGAL

Study type: Observational

Funder types: Other

Identifiers

NCT03615300

UC18OESI0055

Details and patient eligibility

About

This study was performed to determine the prognosis of patients after cardiac arrest using serum markers called NGAL. The initial NGAL values of patients with post-cardiac arrest syndrome are checked by blood tests, and the long-term neurological prognosis and survival rate are collected after 6 months.

Full description

Serum NGAL is currently being used as a test to determine the likelihood of developing renal failure. However, in a previous study, serum NGAL correlated with neurological prognosis in post cardiac arrest syndrome patients. This prospective study attempts to see the role of serum NGAL as a prognostic factor by including a sufficient number of patients.

Enrollment: 73 patients

Sex: All

Ages: 18+ years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Adult patients who underwent targeted temperature management after out-of-hospital cardiac arrest.

Exclusion criteria

• Patients who did not survived 3 days after cardiac arrest.
• Pre-existing end-stage renal disease or dependence on renal replacement therapy

Trial design

73 participants in 2 patient groups

good neurologic outcome

Description:

Patients with good neurological prognosis after 6 months (CPC 1, 2). serum NGAL is collected.

Treatment:

Diagnostic Test: serum NGAL

poor neurologic outcome

Description:

Patients with poor neurological prognosis after 6 months (CPC 3, 4, 5). serum NGAL is collected.

Treatment:

Diagnostic Test: serum NGAL