Predicting Normal vs. Carrier Status in Euploid Embryos of Translocation Carriers

Reproductive Medicine Associates of New Jersey

Status: Completed

Conditions: Balanced Chromosomal Translocation

Study type: Observational

Funder types: Other

Identifiers

NCT02178865

RMA-2014-01

Details and patient eligibility

About

The purpose of this study is to assess the accuracy of predicting the normal or carrier status of human embryos resulting from in vitro-fertilization (IVF) from patients carrying a balanced translocation.

Full description

This study aims to evaluate the validity of using informative SNPs to distinguish balanced from normal embryos. This will involve acquiring material from families to set phase for informative SNPs, evaluation of existing and new embryo SNP array data, and follow up analysis of children born after applying the procedure.

Enrollment: 11 patients

Sex: All

Ages: 7+ years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

• patients with balanced translocations who have undergone IVF

Exclusion criteria

• those who do not wish to know their child(s) karyotype

Trial design

11 participants in 1 patient group

translocation carrier

Description:

balanced translocation carriers who have undergone IVF