Predicting Outcome in Cervix Carcinoma: a Prospective Study (POCER)

Maastricht Radiation Oncology

Status: Completed

Conditions: Cervical Cancer

Study type: Observational

Funder types: Other

Identifiers

NCT01825005

12-4-008

Details and patient eligibility

About

The main aim is to validate and improve the predictive model for survival and toxicity in patients with cervical cancer through multicentric prospective data collection. The data contain information on patient, tumor and treatment characteristics. For this study, additional health related QOL scores will be assessed using the EORTC Quality of Life Questionair-CX24 and C30. The long term aim, beyond this specific study, is to build a Decision Support System based on the predictive model validated in this study.

Enrollment: 423 patients

Sex: Female

Ages: 18+ years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• histological or cytological proven cervical cancer
• informed consent according to national rules

Exclusion criteria

• no histological or cytological proven cervical cancer
• no informed consent according to national rules

Trial design

423 participants in 4 patient groups

group 1:surgery

Description:

treatment = surgery only

group 2: radiotherapy

Description:

treatment = radiotherapy only

group 3: RT and CT, and/or hyperthermia

Description:

treatment= radiotherapy combined with chemotherapy and/or hyperthermia

group 4: stage IVb , any treatment

Description:

cervical cancer stage IV b, treatment = any systemic or radiation therapy and supportive care