Predicting Relapse After Cocaine Inpatient Cessation (QUIT-COC)

Assistance Publique - Hôpitaux de Paris

Status: Completed

Conditions: Cocaine Dependence; Cocaine Use Disorder

Treatments: Procedure: Brain MRI imagery

Study type: Observational

Funder types: Other

Identifiers

NCT02416050

2014-A01169-38 (Other Identifier)

P120125

Details and patient eligibility

About

Can brain MRI at entry of cocaine inpatient cessation attempt predict relapse during a three month follow-up ? Hypothesis : White matter losses in the prefrontal cortex are associated with relapse to cocaine use.

Full description

A multivariate model using MRI parameters, craving score, impulsivity score, and neuropsychological testing results will be tested to predict relapse or continuous abstinence three month after cocaine inpatient cessation attempt.

Enrollment: 87 patients

Sex: All

Ages: 18+ years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• cocaine dependent patient requiring inpatient cessation
• 18 years old and older
• giving his/her consent to come back for visits up to three months
• having a social insurance

Exclusion criteria

• minor
• under guardianship
• restraint hospitalization
• contraindication to brain MRI
• pregnant women