Predicting Response to Intra-Articular Corticosteroid Injection in Patients With Osteoarthritis of the Glenohumeral Joint

University of Florida

Status and phase: Terminated; Phase 4

Conditions: Osteoarthritis of the Glenohumeral Joint

Treatments: Procedure: intraarticular corticosteroid injections (IACSI); Drug: corticosteroid injections; Device: Ultrasound

Study type: Interventional

Funder types: Other

Identifiers

NCT03232749

IRB201700603-A

OCR18320 (Other Identifier)

Details and patient eligibility

About

This study will examine the effectiveness of a single cortisone injection in patients with shoulder osteoarthritis over a 6-month period, and identify clinical and radiographic factors to help predict how a patient with shoulder osteoarthritis will respond to a cortisone injection utilizing ultrasound guidance.

Full description

The purpose of this study is to assess the effectiveness of intraarticular corticosteroid injections (IACSI) for glenohumeral arthritis by 1) through patient-reported outcomes and 2) identifying clinical and radiographic predictors of IACSI success.

Enrollment: 25 patients

Sex: All

Ages: 18 to 100 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Patients with a diagnosis of symptomatic primary osteoarthritis of the shoulder will be recruited from the patient population seeking treatment at the Orthopaedics Sports Medicine Institute.
• those who have failed previous treatment including over-the-counter analgesics and activity modification
• have elected to receive a medically-indicated, ultrasound-guided IACSI in the shoulder.

Exclusion criteria

• Patients will be excluded from the study for any of the following reasons:
• Post traumatic osteoarthritis
• Inflammatory osteoarthritis
• Imaging confirmed rotator cuff tear
• Prior ipsilateral shoulder surgery
• Memory loss or inability to complete study measures
• History of allergy to injection medications
• Diabetic patients with patient-reported fasting blood glucose >200
• Prior injection in the ipsilateral shoulder within three months

Trial design

Primary purpose: Treatment

Allocation: N/A

Interventional model: Single Group Assignment

Masking: None (Open label)

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25 participants in 1 patient group

symptomatic primary osteoarthritis of the shoulder

Other group

Description:

Subjects enrolled into the study will be those who have failed previous treatment including over-the-counter analgesics and activity modification, and have elected to receive a medically-indicated, ultrasound-guided IACSI in the shoulder

Treatment:

Drug: corticosteroid injections

Device: Ultrasound

Procedure: intraarticular corticosteroid injections (IACSI)