Prediction Model of Occult Omental Metastasis in Patients With Gastric Cancer

Northern Jiangsu People's Hospital

Status: Enrolling

Conditions: Gastric Cancer; Omental Metastasis

Treatments: Other: Without any intervention, we only divided gastric cancer patients into two groups based on postoperative pathology, and analyzed their basic characteristics and risk factors

Study type: Observational

Funder types: Other

Identifiers

NCT06405009

NorthernJiangsu003

Details and patient eligibility

About

A complete omentectomy is typically recommended during radical total gastrectomy for gastric cancer, though its impact on survival remains unclear. This study aimed to assess the frequency and risk factors of metastases in the greater omentum in gastric cancer patients undergoing gastrectomy. It will involve a single prospective cohort of consecutive patients who underwent total gastrectomy with complete en bloc omentectomy and modified D2 lymphadenectomy. Post-surgery, the omentum will dissect from the gastrectomy specimen beyond the gastroepiploic vessels and examine separately for pathological assessment. The primary outcome will focus on the detection of omental metastases.

Enrollment: 450 estimated patients

Sex: All

Ages: 18 to 80 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

1. pathological confirmation of gastric cancer
2. eligibility for surgical intervention
3. undergoing first rectal cancer surgery
4. acquisition of written informed consent from patients and their families
5. no history of hypertrophic scar or allergic predispositions

Exclusion criteria

1. absence of postoperative pathology of the omentum
2. diagnosis of multiple primary malignancies
3. intraoperative discovery of widespread implant metastases within the abdominal cavity
4. severe comorbidities

Trial design

450 participants in 2 patient groups

patients with omental metastases

Treatment:

Other: Without any intervention, we only divided gastric cancer patients into two groups based on postoperative pathology, and analyzed their basic characteristics and risk factors

patients without omental metastases

Treatment:

Other: Without any intervention, we only divided gastric cancer patients into two groups based on postoperative pathology, and analyzed their basic characteristics and risk factors