Prediction of Cardiovascular Events in Vulnerable Patients Following Acute Coronary Syndrome

Mayo Clinic

Status: Completed

Conditions: Acute Coronary Syndrome

Treatments: Other: EndoPAT testing (non invasive device); Other: WatchPAT testing (non-invasive device)

Study type: Interventional

Funder types: Other

Identifiers

NCT01500902

09-000047

Details and patient eligibility

About

The purpose of this study is to determine if testing patients for endothelial dysfunction will help identify which patients are more likely at risk to have another heart attack in the future. Study participants will undergo mental stress testing while at the same time being connected to a device that measures endothelial function via the Endopat device. These same participants will also undergo a sleep study via the Watchpat device.

Enrollment: 101 patients

Sex: All

Ages: 18+ years old

Volunteers: No Healthy Volunteers

Inclusion criteria

1. Patients undergoing revascularization by percutaneous intervention (PCI) for Acute Coronary Syndrome (ACS) at Mayo (STEMI and NonSTEMI patients)
2. Age greater than 18

Exclusion criteria

1. Patients likely not to complete the study due to co-morbid conditions (end stage renal disease; liver failure; malignancies)
2. Inability to sign a consent form or availability for follow up
3. Patients unable to tolerate the blood pressure cuff inflation on both arms
4. patients with tremors
5. sustained non-sinus cardiac arrhythmias
6. acrylic finger nails
7. permanent pacemaker
8. color blindness
9. use of alpha blockers and short acting nitrates < 3 hours before study
10. Federal Medical Center inmates

Trial design

Primary purpose: Diagnostic

Allocation: N/A

Interventional model: Single Group Assignment

Masking: None (Open label)

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101 participants in 1 patient group

vascular testing

Other group

Description:

We are assessing vascular testing in patients presenting with acute coronary syndrome to determine if this type of testing will help identify which patients are more likely at risk to have another heart attack.

Treatment:

Other: WatchPAT testing (non-invasive device)

Other: EndoPAT testing (non invasive device)