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Prediction of Fetal Lung Maturity

A

Assiut University

Status

Completed

Conditions

Fetal Distress

Treatments

Radiation: Fetal adrenal gland volume:
Radiation: fetal lung volume
Radiation: pulmonary artery resistance index

Study type

Interventional

Funder types

Other

Identifiers

NCT03159234
17100188

Details and patient eligibility

About

Diabetes is the most common medical complication of pregnancy in the united states four to five percent of pregnancies are complicated by diabetes.

Pregestational diabetes (diabetes diagnosed before pregnancy, type 1 or type 2 diabetes mellitus) comprises approximately 13 percent of all diabetes in pregnancy, while gestational diabetes ( diabetes with onset or first recognition in pregnancy) comprises the remaining 87 percent . The prevalence of pregestational diabetes has been increasing due to the increasing prevalence of type 2 diabetes in women of reproductive age . The mainstay of the medical management of pregestational diabetes involves frequent monitoring of blood glucose levels with adjustment of diet and insulin therapy to achieve normoglycemia. Normoglycemia is important because maintenance of maternal blood glucose concentration at or near normoglycemic levels decreases the likelihood of adverse pregnancy outcomes, such as miscarriage , congenital anomalies , macrosomia and fetal death.

Enrollment

54 patients

Sex

Female

Ages

20 to 40 years old

Volunteers

No Healthy Volunteers

Inclusion criteria

  • All pregnant diabetic women
  • 37 weeks gestational age .

Exclusion criteria

  • Women before 37 and after 39 weeks gestational age
  • Pregnancies with known fetal anomalies that may potentially affect the lung maturity .
  • Multiple pregnancies.
  • Women received steroids for lung maturation after ultrasound image acquisition and before delivery .
  • Women with premature rupture of membranes (prom)
  • Pregnancies complicated by medical disorders other than diabetes mellitus .
  • Failure to obtain an informed consent .

Trial design

Primary purpose

Diagnostic

Allocation

N/A

Interventional model

Single Group Assignment

Masking

None (Open label)

54 participants in 1 patient group

Diabetic pregnant women
Other group
Treatment:
Radiation: fetal lung volume
Radiation: Fetal adrenal gland volume:
Radiation: pulmonary artery resistance index

Trial contacts and locations

1

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Data sourced from clinicaltrials.gov

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