Prediction of Fluid Responsiveness From Passive Leg Raising Induced Changes in Perfusion Index and Pleth Variability Index

Institute of Mountain Emergency Medicine

Status: Completed

Conditions: Fluid Responsiveness

Treatments: Diagnostic Test: Passive Leg Raising Test

Study type: Interventional

Funder types: Other

Identifiers

NCT03499860

06

Details and patient eligibility

About

The aim of the study is to evaluate whether changes in Perfusion Index (PI) and Pleth Variability Index (PVI) during passive leg raising test can predict fluid responsiveness in spontaneously breathing patients.

Fluid responsive patients are defined as showing an increase in cardiac output >10% during a passive leg raising test, measured semi-invaseively with FloTrac® (Edwards LifeSciences. Irvine, United States).

Enrollment: 51 patients

Sex: All

Ages: 18+ years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Adult patients admitted to the intensive or intermediate care unit after abdominal surgery (including urological and gynecological surgery performed in laparotomy)
• Spontaneous breathing
• Arterial line already in place
• Oral and written informed consent obtained

Exclusion criteria

• Age <18 years
• Abdominal trauma as the reason for surgery
• Missing informed consent

Trial design

Primary purpose: Diagnostic

Allocation: N/A

Interventional model: Single Group Assignment

Masking: None (Open label)