Prediction of Fluid Responsiveness in Atrial Fibrillation Patients Who Underwent Valvular Heart Surgery: Peep-induced Increase in Central Venous Pressure vs. Passive Leg Raising

Yonsei University

Status: Completed

Conditions: Valvular Heart Surgery

Treatments: Procedure: passive leg raising(PLR); Procedure: peep induced CVP

Study type: Interventional

Funder types: Other

Identifiers

NCT02224378

4-2011-0686

Details and patient eligibility

About

Dynamic indices of preload depending on the heart-lung interaction require sinus rhythm and cannot be applied to patients with atrial fibrillation. PEEP-induced increase in central venous pressure (CVP) was shown to be a valid predictor of fluid responsiveness after cardiac surgery in patients with sinus rhythm, and was speculated to be of value in patients with rhythm other than sinus. The aim of this study is to assess the predictability of PEEP-induced increase in CVP and passive leg raising (PLR)-induced changes in stroke volume index (SVI) on fluid responsiveness in patients with atrial fibrillation following valvular heart surgery.

Enrollment: 44 patients

Sex: All

Ages: 20+ years old

Volunteers: No Healthy Volunteers

Inclusion criteria

1. age ≥20
2. atrial fibrillation patients who underwent elective valvular heart surgery

Exclusion criteria

1. age < 20
2. LV ejection fraction < 40%
3. any pulmonary disease
4. end stage renal disease
5. high intrabdominal pressure patient
6. contraindication of passive leg raising
7. deep vein thrombosis

Trial design

Primary purpose: Diagnostic

Allocation: Non-Randomized

Interventional model: Parallel Assignment

Masking: None (Open label)

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44 participants in 2 patient groups

peep induced CVP

Experimental group

Treatment:

Procedure: peep induced CVP

passive leg raising(PLR)

Active Comparator group

Treatment:

Procedure: passive leg raising(PLR)