Prediction of Hemodynamic Reactivity During General Anesthesia Using Analgesia/Nociception Index (ANI)

Hôpital Edouard Herriot

Status: Completed

Conditions: Anesthesia

Study type: Observational

Funder types: Other

Identifiers

NCT01839513

CPP 2013-021B

Details and patient eligibility

About

The aim of this study is to evaluate the performance of Analgesia/Nociception Index for the prediction of hemodynamic reactivity in adult patients undergoing ear-nose-throat or lower limb orthopedic surgery on desflurane/remifentanil general anesthesia.

Full description

Measurement of analgesia/nociception index at different time points during procedure and assessment of analgesia/nociception index to predict hemodynamic reactivity by building receiver observer's characteristic curve.

Enrollment: 100 patients

Sex: All

Ages: 18 to 75 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Age 18-75 years
• Ear-nose-throat or lower limb surgery
• General anesthesia using desflurane and remifentanil

Exclusion criteria

• Age <18 yrs or >75 yrs
• Arrythmia
• Preoperative use of B-blockers
• Administration of anticholinergic drugs or neuromuscular blockade reversal in the 20 previous minutes
• Psychiatric diseases
• Autonomic nervous system disorders (epilepsy)